![]() ![]() The correlation between TcB and TSB results in previous studies was strong ( r = 0.835 p < 0.0001), but this study did not measure bilirubin levels during phototherapy. Several studies on transcutaneous and Bilistick bilirubin measurements have been conducted to assess the validity of both devices. With regards to its cost, the Bilistick System is considerably cheaper than the non-invasive transcutaneous bilirubinometer (TcB) €1300 for transcutaneous bilirubin (JM 103) compared to €600 for Bilistick device (2016 Version) and €1.5 for each test strip and transfer pipette. Compared to TSB, which requires large volumes of blood, the Bilistick System requires only 25 μL of capillary blood. In this study, we will be focusing on the Bilistick System. Currently, there are several alternatives for measurement of bilirubin levels. However, this measurement is an invasive procedure that poses a higher risk of infection, pain, and requires a rather large amount of blood. Serum bilirubin measurement is a gold standard for measuring total serum bilirubin (TSB) levels for both detection and evaluation during phototherapy. The risk increases especially in preterm infants with lower blood volume and altered immune status. However, regular blood taking can cause problems such as anemia and increased risk of infection in newborns with hyperbilirubinemia. During the course of phototherapy, it is necessary to monitor the bilirubin levels periodically until phototherapy is completed in order to prevent overtreatment. Phototherapy is still the primary treatment to prevent further complications for newborns with hyperbilirubinemia, especially for premature infants who have a higher risk of bilirubin encephalopathy. Hyperbilirubinemia in neonates often develops in the first week of life, ranging in frequency from 60% in term and 80% in preterm infants. Hyperbilirubinemia is one of the most common problems arising in the neonatal period. TcB tends to overestimate while Bilistick underestimates TSB. Conclusionsīoth methods are reliable for measuring TSB before, during, and after phototherapy in preterm infants. Methodsīilirubin was measured by using TcB and Bilistick in 94 preterm infants in RSCM Jakarta Neonatal Ward from October 2016 to March 2017, with gestational ages of < 35 weeks, before phototherapy and after 24 and 48 h of phototherapy. We assess the agreement of Transcutaneous Bilirubinometer (TcB) and Bilistick bilirubin measurements with standard TSB measurement in preterm infants receiving phototherapy. This study compares the minimally invasive Bilistick and a noninvasive method with standard Total Serum Bilirubin (TSB) measurement in preterm newborns receiving phototherapy. ![]()
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